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Slesinger, Paul A

Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA

TitleYearPMID
Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. PDF 2025 41083468
Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder. preprint 2024 39149227
Polygenic risk for alcohol use disorder affects cellular responses to ethanol exposure in a human microglial cell model. 2024 39514655
Upregulated GIRK2 Counteracts Ethanol-Induced Changes in Excitability and Respiration in Human Neurons. 2024 38350999
Upregulated GIRK2 counteracts ethanol-induced changes in excitability & respiration in human neurons. preprint 2024 36993693
5. Collaborative Study on the Genetics of Alcoholism: Functional genomics. 2023 37533187
Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. 2023 36207584
The collaborative study on the genetics of alcoholism: Genetics. 2023 37387240
Advances in Targeting GIRK Channels in Disease. 2021 33468322
Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells? 2018 29897633
An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells. 2017 28757165
Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol. 2017 28676630
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells. 2016 26626326
Structural Insights into GIRK Channel Function. 2015 26422984
Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics. 2014 24611054
Sorting nexin 27 regulation of G protein-gated inwardly rectifying K⁺ channels attenuates in vivo cocaine response. 2014 24811384
Molecular mechanism underlying ethanol activation of G-protein-gated inwardly rectifying potassium channels. 2013 24145411
Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. 2010 20389305
A discrete alcohol pocket involved in GIRK channel activation. 2009 19561601
Addictive drugs modulate GIRK-channel signaling by regulating RGS proteins. 2008 18790542
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