The effect of differential response to feedback (loss vs. reward) was over twice as large for males, although this finding emerged in a high-risk sample and may not generalize to low-risk youth. On the other hand,Santesso et al. (2011) reported that females displayed a larger FRN than males, which was accounted for by greater response to “win” feedback. The remaining three developmental studies of the FRN did not include sex in their reported statistical analyses (Eppinger et al., 2009; Hämmerer et al., 2011). Overall, emerging work clearly warrants inclusion of sex as a factor in reward processing studies.
