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Chunk #6 — Introduction

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Mechanisms in the relation between GABRA2 and adolescent externalizing problems.
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Two particularly important facets of disinhibition in adolescence are sensation seeking and impulsivity, which have been differentiated based on neurobiological and developmental evidence [32]. Sensation seeking is an earlier indicator of a socioemotionally driven reward system defined as the tendency to seek out novel/varied experiences and take risks, while impulsivity is an indicator of a deficit in a later developing cognitive control system defined as lack of planfulness and self-control [32]. These two types of dis-inhibition were also found in Whiteside and Lynam's [33] model of impulsivity, corresponding with sensation seeking (a tendency to seek out exciting and novel situations) and lack of premeditation (an inability to carefully think and plan).