Preliminary SNP selection identified 78 variants meeting criteria for genome-wide or suggestive significance in either of two large meta-analyses of BMI, 43 from Thorleifsson et al. (2009) and 35 from Willer et al. (Thorleifsson et al. 2009; Willer et al. 2009). Thorleifsson and colleagues report genome-wide significant (p < 1.6E-07) associations with 29 SNPs in 11 chromosomal regions, using a discovery sample of n = 34,416 and replication sample of n = 5,586. The Willer et al. meta-analysis detected 8 genome-wide significant (p < 5.0E-08) SNPs in first- and second-stage samples of n = 32,387 and n = 54,316, respectively. Only variants in or near FTO and MC4R were found to be genome-wide significant in both meta-analyses. The remaining genetic loci were suggestive in the opposing metaanalyses (p < 0.05) except rs7138803 on 12q13 (p = 0.14). Significance level for one SNP, rs10938397 on 4p12, could not be compared between meta-analyses because there was no corresponding proxy SNP. Of the 78 variants catalogued, 29 had matching SNPs on the Affymetrix 6.0 array. For the 49 SNPs not present, proxies (45
