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Chunk #21 — EROs and Alcoholism — Theta and delta EROs in alcoholics and high-risk individuals — Go/NoGo task

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Event-Related Oscillations in Alcoholism Research: A Review.
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The Go/NoGo task has been most widely used to assess response inhibition, in which the subject withholds his/her response for one set of stimuli (“NoGo” trials) while responding to another set of stimuli (“Go” trials). The task can be either a type of ‘reverse oddball’, with more trials for the Go condition, or have equal trials in both Go and NoGo conditions [146]. Only a few studies have analyzed EROs using the Go/NoGo paradigm to investigate alcoholism. Using an equal probability visual Go/NoGo task, Kamarajan et al. [99] reported deficient delta and theta oscillatory activity in abstinent alcoholics. This reduction in delta and theta EROs in alcoholic subjects was found in the frontal region, particularly during NoGo trials [99]. To examine whether or not these deficits anteceded the development of alcoholism, the authors studied offspring of alcoholic parents and found that these high-risk subjects manifested significantly decreased ERO activity in delta (1-3 Hz), theta (4-7 Hz), and low alpha (8-9 Hz) bands during the NoGo condition, as well as reduced delta and theta activity during the Go condition. This study