encoding the calmodulin-lysine N-methyltransferase (P=2.86×10−9; Q=0.0017) with LD extending into several adjacent genes. Allelic frequencies were consistent across studies, ranging from 0.32 to 0.36. Both of these SNPs were imputed with very high quality across studies (R2>0.93). As indicted in the forest plots (Supplementary Figure S1), no heterogeneity of effects was observed for either SNP. Figure 3 displays the regional SNP plots for these two genome-wide significant loci.
