relationship due to the inclusion of the Kuusamo and Geneva samples. One is an isolate and the other is a highly heterogeneous international metropolis. The λ values between CEU and the other samples (Table 2) were smaller than those obtained using the Northern German sample as a reference, chosen as the nearest to the origin of CEU sample, and the correlation between geography and λ with CEU was only r2 = 0.251 (p-value 0.017). Both results probably reflect the higher genetic variability in the CEU sample.
