with p and and a collection of background pairs (BP) whose members were not associated with p. Finally, ROC analysis was performed wherein the connectivities between members of Ep were compared to that between members of Bp at different threshold values for connectivity t ranging from (0, 100). At each threshold we computed true positive rates (TPR) as the fraction of Ep that were connected, and false positive rates (FPR) as the fraction of Bp that were connected, thereby generating an ROC curve from which an AUC was derived.
