Moreover, cue-specific fear suggests altered AMY function (Phillips & LeDoux, 1992) and is consistent with known effects of alcohol and amygdala-based fear responses (Agoglia & Herman, 2018; McCool, Christian, Diaz, & Lack, 2010). The AMY also regulates positive reinforcing effects of alcohol (Besheer et al., 2003; Besheer, Fisher, Cannady, Grondin, & Hodge, 2012; Cannady et al., 2017; Salling et al., 2016; Schroeder et al., 2003) and cue-induced relapse to alcohol-seeking behavior (Cannady, Grondin, Fisher, Hodge, & Besheer, 2011; Salling et al., 2017; Schroeder et al., 2008), which suggests common neuroanatomical mechanisms of AD and alcohol addiction.
