In summary, our analysis demonstrated: i) a link between pre-treatment blood glucose levels and pre-treatment heavy drinking, pointing out the role of heavy drinking as a metabolic and cardiovascular risk factor via increased glucose levels; ii) a link between pre-treatment blood glucose levels and during-treatment heavy drinking, suggesting a role of glucose in predicting heavy alcohol consumption. Although further work needs to be done to assess the possible involvement of glucose in the alcohol seeking behavior, these results suggest that elevated glucose and heavy drinking may be affected by a common mechanism and manipulations affecting glucose regulation may influence alcohol consumption.
