One of the by-products of the procedure is a list of genes that are estimated to have non-zero effects. We present the gene lists for λ = 1 in Table 2. Out of the 4880 genes, only 21 are estimated to have nonzero effects. Of the genes that are overexpressed in prostate cancer relative to benign prostate tissue, the early growth response (Hs. 326035/301865), feline sarcoma viral oncogene homolog (Hs.81665), T-cell receptor gamma locus (Hs. 112259), and fatty acid synthase (Hs.83190) have been seen by other investigators to be upregulated in prostate cancer, as in Table 3. The other genes on the list could represent false positives or genes whose joint effect is predictive of cancer status.
