Chunk #16 — Basic methodology of genetic epidemiology: an overview of twin studies — Principle 3: The environment moderates the importance of genetic influences
reflect differences in availability of alcohol, a range of possible different role models, neighborhood stability, and community-level monitoring across different areas. The environments for which there are demonstrated moderating effects on genetic influences in adolescence largely appear to reflect differential social control and/or opportunity, resulting in differential expression of individual predispositions (Shanahan and Hofer, 2005).