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Chunk #7 — Results

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A genome-wide association study of neuroticism in a population-based sample.
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(Figure 1c, Table 1). The strongest signal (p≈10−7) was at a genotyped SNP, rs9561329; EPQ score tends to increase with age for carriers of the minor allele, and decreases for non-carriers (Figure 2). Conditional regression analyses revealed that the signal at each of the SNPs reported in Table 1 effectively disappeared when the most strongly-associated SNP at that locus was included as a predictor in the regression, suggesting at most one causal variant underlying each signal.