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Chunk #0 — Introduction

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Dipole source analysis of auditory P300 response in depressive and anxiety disorders.
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P300 has attracted great interest of psychiatrists and psychologists because of its correlation with cognition and attention. Reduced magnitude of P300 component and reduction of coherences during oddball paradigm have been observed in patients with psychiatric disorders like schizophrenia (Hegerl et al. 1995), and Alzheimer’s disease patients (Ito et al. 1990; Guntekin and Basar 2010). A further study suggests P300 parameters and topography can be used to differentiate between forms of dementia, as well as between dementia and pseudodementia (Maurer and Dierks 1991).