RICOPILI allows for additional features and modules (see Supplementary Information). Including, (i) reference builder: builds reference data for genotype imputation from publicly accessible reference panels (Supplementary Fig. S6), (ii) replication of GWAS: using external summary data or those generated by RICOPILI and (iii) polygenic leave-one-out analysis: where each input dataset is used as a hold out and polygenic risk prediction is done iteratively across hold out data. All helper scripts and modules are saved in a centralized location specified by the user within a folder called rp_bin/and logging files with *_info suffix are also available.
