Therefore, monitoring rates of alcohol-induced deaths over time within sociodemographic subgroups of the US population is critical for targeting preventive health and health care resources.6 In this serial cross-sectional study, we analyzed patterns of alcohol-induced mortality within the United States between 2000 and 2016. We examined trends in alcohol-induced death rates over time, comparing results by demographic characteristics including sex, race/ethnicity, age, county-level socioeconomic status (SES), and geographic location.