their relatives5. While increased connectivity observed among individuals with higher SCZ PRS may seem counterintuitive to many dysconnectivity hypotheses in psychotic illness, several previous studies have found similar patterns of increased connectivity among those with SCZ and their relatives5,50–54. For example, Kam et al.5 found that individuals with SCZ exhibited greater connectivity, and emphasized that, as in our study, EEG was recorded during rest as opposed to during a cognitive task. They suggest that this pattern of increased neural synchronization may reflect network activity in the resting-state that is less selectively organized among individuals at risk for SCZ, consistent with suggestions that SCZ may be associated with inefficient neural processing55–57.
