Recall from the main text that the PGI Repository aims to overcome four obstacles: (1) Constructing PGIs can be time-consuming and requires specialized knowledge; (2) Researchers face administrative hurdles in accessing all the genome-wide summary statistics for constructing PGIs; (3) Publicly available summary statistics may include the target dataset (which should be omitted when constructing the PGI); and (4) PGIs are often constructed with a variety of methods and idiosyncratic analysis decisions.
