Chunk #28 — Results

Source

Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence.

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On the contrary, the RV rs146792012 in GRIN2B was observed to be significantly associated with opioid initiation (P=0.0155) in AAs. However, possibly due to the small sample size and low MAF, no significant association was found for OD among opioid users (P=0.158).