Mice were housed (3-5 per cage) in climate controlled (22 ± 2°C) rooms on a normal 12 hour light cycle (lights on 7 AM) with food and water available ad libitum until the day of testing. The mice were separated into individual cages the morning prior to testing. These procedures were approved by the Gallo Center Institutional Animal Care and Use Committee (Emeryville, CA) and were in accordance with National Institutes of Health guidelines for the Humane Care and Use of Laboratory Animals.