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Chunk #17 — METHODS — REGRESSION ANALYSIS

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A comparison of approaches to account for uncertainty in analysis of imputed genotypes.
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We used regression analysis to test the effectiveness of multiple summaries of the imputed genotypes. Let pki denote the conditional (“posterior”) probabilities for the imputed genotypes of individual i (1,….,n), where k (0,1,2) indexes the genotype by its label. We evaluated the performance of the following three summaries of the genotype probabilities conditional on the observed data: