Subjects provided saliva samples for DNA extraction and genotyping and underwent structural MRI scans. A total of 326 subjects were consented, 305 passed quality control checks for CNV detection and of those 305, 283 passed further quality checks on their structural MRI scans. 84 of the 283 subjects were female age 33.02 ± 10.73 and 199 were male age 31.97 ± 9.42. Because our subjects were drawn from two separate studies, the final sample included 131 treatment seeking individuals and 152 treatment naive individuals. Structural data from a control cohort of 75 subjects drawn from a separate schizophrenia study were also used. Control subjects were screened using the SCID for DSM-IV, subjects were excluded who were diagnosed with alcohol and substance abuse/dependence, medical, psychiatric or neurological illnesses (Segall et al., 2009). All of the control subjects provided written informed consent. Forty eight of subjects were male and subject age was 32.04 ± 11.51.
