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Chunk #3 — Methods and Materials — Subjects

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High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk.
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assigned to the AA sample. To maintain power for family-based analyses, final ancestry assignment was based on the majority of individual family members. Families with an equal distribution were assigned to the most diverse group (AA). This analysis excluded subjects who were not assignable to either the EA or AA groups. There were 2794 subjects with genome-wide association study data available for this analysis, 67% EA (1872 subjects from 559 families) and 33% AA (922 subjects from 219 families). Among the subjects, 51% were female and 49% were male.