pathways and transcription factors were found between the continuous access and water control groups, whereas no significant differences were observed in the ACB between the multiple scheduled access and the water control groups, when measured the day after the last drinking episode. Studies on changes in gene expression within discrete regions of the extended amygdala following alcohol drinking have not yet been undertaken. Since the extended amygdala is an important system involved in regulating alcohol drinking and dependence-induced drinking (Koob and LeMoal, 2008; Koob et al., 1998; McBride, 2002; Roberts et al., 1996), it would be important to determine the effects of alcohol drinking on gene expression changes within this system.
