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Chunk #30 — Discussion — Conclusion

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Temperament and externalizing behavior as mediators of genetic risk on adolescent substance use.
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However, we are still far from being able to provide recommendations for individualized treatments based on genetic makeup. With the current state of knowledge, genetic screenings are likely to provide minimal gain in the effectiveness of interventions with potential costs. For example, genetic screening that connects a genetic disposition to externalizing behavior and substance use could lead to stigmatization and discrimination (Chhangur, Weeland, Matthys, & Overbeek, in press).