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Chunk #18 — Methods — Measures — OXTR Genetic Risk Score

Source
Transactions Between Substance Use Intervention, the Oxytocin Receptor (OXTR) Gene, and Peer Substance Use Predicting Youth Alcohol Use.
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SNP, indicating that rs7632287 could be used as a proxy (R2 = .95;1000 Genomes Project Consortium, 2012). SNPs were coded so that 2 indicated homozygous for the risk allele (high), 1 indicated heterozygous for risk allele (medium), and 0 indicated homozygous for the non-risk allele (low). These values were summed for each individual to make up the OXTR genetic risk score (range = 2-8, M(SD) = 5.76 (1.11)).