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Chunk #41 — Discussion

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The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network.
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Overall, it is unclear whether alcohol directly affects Cd14 expression and through which mechanisms, but our findings present potential biological processes that may be involved. Although we identified proinflammatory cascades, LPS binding, and apoptosis as potential mechanisms through which Cd14 regulates ethanol response, the majority of the genes we identified as potential players in the Cd14 network have immune-related functions.