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Chunk #63 — ONLINE METHODS — Variance explained by SNPs in proximity to the top associated SNPs

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Defining the role of common variation in the genomic and biological architecture of adult human height.
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1.3%), 25.7% (s.e. = 1.8%) and 29.5% (s.e. = 2.2%) of phenotypic variance, respectively. We then applied a regression-based approach28 to adjust for LD between SNPs. The estimates of variance explained after LD-adjustment were slightly higher than those without adjustment, and the ratio of between the estimates with and without LD-adjustment was consistently ~1.05 regardless of the window size (Supplementary Fig. 6a). However, the difference is small.