exhibit cognitive deficits that correspond to hippocampal and PFC volume reduction despite only a few years of excessive drinking [40-45]. The consistent reports of degeneration in adolescent hippocampus are intriguing as adults with AUDs do not reliably show hippocampal degeneration [46]. Given the role of the PFC and hippocampus in behavioral inhibition systems, alcohol-induced damage to these regions could increase impulsive behavior, lead to poor-decision making and therefore promote further excessive alcohol consumption [47].
