After tagging using HaploView, a set of 42 tagSNPs (Supplementary table 4) was selected including two SNPs that were force-included (steps 10A(ii) and 10B(iii)). The selection of SNPs in the force list was based on the dbSNP database in which a high proportion of the entries are neither validated nor have been genotyped in the HapMap project. This explains why only two of the 12 SNPs in the list enter into the final selection of tagSNPs.