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Chunk #58 — Materials and Methods — Bayes factor computation

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Bayesian test for colocalisation between pairs of genetic association studies using summary statistics.
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A Bayes Factor for each SNP and each trait 1 and 2 was computed using the Approximate Bayes Factor (ABF, [20]). Wakefield's method yields a Bayes factor that measures relative support for a model in which the SNP is associated with the trait compared to the null model of no association.