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Chunk #33 — Results — Risk Prediction by ERS and its Associations with Lipid Outcomes

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Environmental risk score as a new tool to examine multi-pollutants in epidemiologic research: an example from the NHANES study using serum lipid levels.
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The ERS’s from single-pollutant models ranged from −0.068 to 0.239 (mean±SD = 0.090±0.043) for total cholesterol (fit as a continuous outcome (log-transformation). Same for other outcomes); −0.226 to 0.205 (0.030±0.057) for HDL; −0.059 to 0.195 (0.088±0.029) for LDL; and −1.278 to 0.563 (–0.445±0.228) for triglycerides. Those from a multi-pollutant model ranged from −0.009 to 0.135 (0.058±0.019) for total cholesterol; −0.013 to 0.152 (0.061±0.022) for HDL; −0.054 to 0.183 (0.086±0.027) for LDL; and −0.291 to 0.339 (–0.009±0.082) for triglycerides (Table S4). The ERS2 were generally smaller than the ERS1 because of more inverse associations in ERS2.