The Collaborative Study on the Genetics of Alcoholism (COGA)'s prospective study began its multi-site data collection in 2004 and ended in 2019. Details on data collection and procedures have been published previously (Dick et al., 2023). Briefly, 3715 offspring (14 495 total assessments) from families densely affected with AUD and community comparison families who had at least one parent interviewed in an earlier phase of the COGA study, were enrolled when they were between the ages of 12–22, with new participants added as they reached the age of 12. The COGA study re-assessed participants approximately every two years. A comprehensive battery was administered that included the adult Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) or the age-appropriate adolescent SSAGA (cSSAGA-A) and parent version (cSSAGA-P) if participants were under age 18. The SSAGA and cSSAGA-A covered substance use problems as well as other psychiatric disorders, including PTSD. As previously detailed (Meyers et al., 2023), a brain function battery was administered at each assessment. These included neurophysiological measures during resting state. Figure 1 shows available data and which assessments are used
