The frequency of LTH-AD assessed at time 1 and time 2 was 24.9 ± 0.67 and 25.7 ± 0.67%, respectively, in twins that had data for both assessments (4,203 men). As can be seen in Table 1, 695 (67 ± 1.5%) of 1,040 men who met criteria for an LTH-AD diagnosis at time 1, also reported meeting the criteria for the same time period at time 2. Among the 2,772 men who did not meet criteria for LTH-AD at time 1, 383 (14 ± 0.67%) men did when assessed again at time 2. The degree of agreement between the 2 assessments was moderate (κ = 0.54 ± 0.015; tetrachoric r = 0.77 ± 0.014).
