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Chunk #22 — TWIN STUDIES CAN MAXIMIZE POWER IN FUTURE MOLECULAR GENETIC STUDIES

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Twin studies and their implications for molecular genetic studies: endophenotypes integrate quantitative and molecular genetics in ADHD research.
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Twin studies have helped to decrease the number of phenotypes by showing that, although closely related to the behavioral disorder, not all phenotypes are familial. For example, when collected in a laboratory setting, only mechanical motion sensor data from the waist, and not the leg, show significant familial overlap with ADHD, although both body loci show a significant within-person correlation.50