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Chunk #12 — III. The Executive Function of the Prefrontal Cortex

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Alcohol and the prefrontal cortex.
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yes

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on line relevant past memories, (5) plan behavioral sequence based upon these memories and the present relevant stimuli, and (6) encode the preparatory set that leads to motor execution of the appropriate behavior. As noted above, the executive network is thought to be primarily localized within the dorsolateral PFC, and as such this structure is considered to be the ultimate regulator of goal-directed actions. However, the ACC also critically contributes to many aspects of executive functioning by mediating attention to action and conflict monitoring. Also as noted previously, the OFC is extensively connected with sensory cortical areas and limbic structures, and it is thought that this network plays a role in integrating and determining the salience of information about environmental contingencies. It plays a particularly important role in inhibitory control of inappropriate behaviors by relaying processed information to the executive control network of the dorsolateral PFC. Thus, the executive and limbic networks function in concert to orchestrate behaviors particularly related to context and expected outcomes (e.g., expectation of a goal-directed action).