This study represents the largest (N=25,781) investigation on the genetic architecture of antisocial behaviour to date. Our meta-analyses of diverse continuous measures of ASB showed that ASB is heritable and highly polygenic and suggests that part of the genetic architecture is sex specific. This is not surprising in view of the sex-influenced phenotypic expression. We also found a strong inverse correlation of ASB with genetic variants for educational attainment and some reproductive traits, and a positive genetic correlation with neuroticism, but not with schizophrenia, bipolar disorder, or ADHD.
