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Chunk #15 — MATERIALS AND METHODS — Experimental Procedures and Outcome Assessments

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Naltrexone modification of drinking effects in a subacute treatment and bar-lab paradigm: influence of OPRM1 and dopamine transporter (SLC6A3) genes.
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As per our previous paradigms and consistent with that of O’Malley (O’Malley et al., 2002), we chose to assess alcohol consumption in the context of an alternative reinforcer, so subjects was given a “bar-credit” of $16 to buy up to 8 mini-drinks ($2 each) or choose to receive any money not spent. Participants had access to one bag of potato chips (28.3 gram/bag) per tray to simulate a normal bar environment and water was also provided.