Chunk #6 — Materials and methods — Statistical analyses — Meta-analysis of GWA results across cohorts

Source

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder.

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yes

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Meta-analysis results at the SNP level were used as the input to compute P-values at the gene level. These analyses were performed with VEGAS2.48,49 A gene with a P-value of 1 × 10−6 or lower is considered genome-wide significant in gene-wide analyses.