excellent psychometric properties and have been shown to be at least moderately heritable (Heath et al. 1997; Bucholz et al. 1994; Agrawal et al. 2009; Grant et al. 2009). Our findings demonstrate that the protection against CSA-associated risk for problematic alcohol use associated with the H2 haplotype is persistent into adulthood. Overall, our results suggest that one or more of the 5 adjacent genes within the H2 haplotype play a major role in the risk for alcohol-related outcomes associated with severe life stressors.
