Efforts by the Schizophrenia Working Group of the Psychiatric Genomics Consortium have recently identified 128 established and novel loci in large samples of cases and controls (Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014). Notably, common variants between schizophrenia, bipolar disorder, autism spectrum disorders and intellectual disability were observed, buttressing the importance of examining common behavioral domains implicated in these disorders, such as social cognition. Classification along these dimensional measures will ultimately yield the mechanistically based diagnostic nomenclature.