For confirmation of the findings regarding borderline traits, univariate ANOVA was conducted in an independent Caucasian population, using the SCID-II Screen questionnaire borderline scale in a Hungarian sample of depressive patients (Table 3). Neither of the DRD2 polymorphisms showed association with BPD traits. On the other hand, the DRD4 -616 C/G SNP showed similar association with BPD traits as observed among the at-risk US young adults. The -616 CC genotype was associated with more severe borderline symptoms using the three genotype groups (p = 0.007). Results were also significant for the combined CC vs CG + GG genotype grouping (p = 0.005). Other dopaminergic polymorphisms did not show any significant associations with the number of borderline symptoms in this clinical sample.
