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Chunk #16 — Method — Statistical analysis

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Predicting alcohol consumption in adolescence from alcohol-specific and general externalizing genetic risk factors, key environmental exposures and their interaction.
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The original distribution of the alcohol use data was highly right skewed. We explore possible optimal Box–Cox transformations in PROC TRANSREG in SAS (SAS Institute, 2008). The results indicated that a log transformation was optimal at stabilizing the variance (i.e. minimizing heteroscedasticity).