The global burden of disease (GBD) framework was initiated by the World Bank report of 1993 [10] and uses information on mortality and disability associated with a given disease to estimate the years of life lost due to premature mortality (YLLs) and the years lived with disability (YLDs). YLLs and YLDs can be summed into disability adjusted life years (DALYs), an overall summary measure of disease burden.
