Chunk #37 — Results — Gender Differences — Association of FH measures with parietal P3 amplitude across gender.

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Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity.

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As shown in Table 3b, in males, all four density measures were significantly associated with low P3 amplitude. Further, FHDrPSND–AUDMaxSxCnt (b=−3.26) presented the most robust association. Among dichotomous measures, only FHFather–AUDDx and FHParent–AUDDx presented significant associations. FHFather–AUDDx (b=−1.34) was most robust. In females, interestingly, none of the dichotomous and density measures were associated with P3 amplitude. Overall, compared to dichotomous measures, albeit only in males, density measures were more consistently associated with P3 amplitude.