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Chunk #24 — Autism: A Complex Genomic Disorder

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CNVs: harbingers of a rare variant revolution in psychiatric genetics.
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ASDs represent a heterogeneous group of disorders that share a set of common characteristics. These include core deficits in social communication and language development that are accompanied by highly restricted interests, stereotypic behaviors or both (Volkmar et al., 2009). ASDs are defined as having an age at onset younger than three. Males have a >3-fold higher risk for ASDs as compared to females (Volkmar et al., 2004).