Chunk #5 — Materials and Methods

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Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence.

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We included the five studies from our prior GWAS meta-analysis23 and 10 additional studies. Details of their study design, genotyping, quality control, 1000 Genomes (1000G) imputation, and analysis are provided in Supplementary Methods and Supplementary Table 1.