transformation patterns derived from them (KEGG RPAIR) and supplementary information on enzyme nomenclature (KEGG ENZYME). The five databases in the chemical information category are collectively called KEGG LIGAND. Note that KEGG DRUG has been moved from the chemical information category (6) to the systems information category to integrate with KEGG DISEASE. Table 1.KEGG databasesCategoryDatabaseContentSystems InformationKEGG PATHWAYPathway mapsKEGG BRITEFunctional hierarchiesKEGG MODULEPathway modulesKEGG DISEASEHuman diseasesKEGG DRUGDrugsGenomic InformationKEGG ORTHOLOGYKEGG orthology (KO) groupsKEGG GENOMEKEGG organismsKEGG GENESGenes in high-quality genomesKEGG SSDBSequence similarities and best hit relationsKEGG DGENESGenes in draft genomesKEGG EGENESGenes as EST contigsChemical InformationKEGG COMPOUNDMetabolites and other small moleculesKEGG GLYCANGlycansKEGG REACTIONBiochemical reactionsKEGG RPAIRReactant pair chemical transformationsKEGG ENZYMEEnzyme nomenclature