Gene set enrichment analysis of SNPs with meta-analysis P ≤ 1 × 10−5, as implemented in DEPICT, indicated a role for two gene sets at FDR < 0.05 in mMDD (Supplementary Table 13): GO terms carboxylic acid binding and CNTN1 PPI subnetwork. No other significant results were observed for tissue enrichment or gene prioritization across MDD definitions.
