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Chunk #46 — Ventral affective circuit — Treatments targeting ventral affective dysfunction in OCD

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Toward a neurocircuit-based taxonomy to guide treatment of obsessive-compulsive disorder.
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In terms of non-invasive neuromodulatory treatments, fMRI-based neurofeedback has successfully been used in non-psychiatric samples to train individuals to increase NAcc activity, which also elicited feelings of positive arousal [161]. Future research testing whether fMRI-based neurofeedback training of the NAcc could benefit OCD patients who show altered reward-related functions will be an important direction in the search for novel OCD treatment targets.